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Event

Lyophilization Technology- Practical Application of the Scientific Principles

March 19, 2012, March 20, 2012, March 21, 2012 iCal


Location: Dublin, Ireland

Course Description:


This course is designed to provide attendees with a practical approach to understanding the scientific and engineering principles of lyophilization. The topics discussed during the course will be presented to explain the physical, physicochemical, biochemical, and engineering principles of the science and engineering behind modern freeze-drying. The practicality of the course allows the attendees to get a firm understanding of the theoretical applications of freeze-drying and how these can be easily used and applied to their day to day lyophilization projects.

Topics covered will include:

  • History of lyophilization
  • Properties of water and ice
  • Supercooling and supersaturation
  • Phase behavior during freezing
  • Thermal characterization
  • Annealing
  • Visco-elastic properties of amorphous phases
  • Collapse phenomena
  • Vacuum physics
  • Product formulation
  • Heat and mass transfer
  • Cycle development
  • End point determination
  • Residual moisture
  • Process scale-up and sonic water vapor flow
  • IQ/OQ/PQ
  • Process control and optimization
  • Fault finding and problem solving of systems and formulations
  • Freeze dryer mechanical and control systems
  • Recipe development
  • Following the process

For more information please visit: http://www.cfpie.com/showitem.aspx?productid=128&source=lsam


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